Dextromethorphan and zyrtec

Dextromethorphan should not be used in pets that are allergic to it. It should be used cautiously in pets with liver disease, skin allergies (atopy), chronic cough, or wet coughs. Dextromethorphan should be used cautiously in pets that are taking MAOIs, or have recently used products such as amitraz containing collars or selegiline.

Find patient medical information for dextromethorphan polistirex oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. dextromethorphan food. Applies to: acetaminophen / dextromethorphan / phenylephrine. Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being ...Dextromethorphan and guaifenesin can be taken together and are even co-formulated in products like Vicks Formula 44 (guaifenesin/dextromethorphan). …Dextromethorphan acts as an antagonist at the glutamate N-methyl-d-aspartate (NMDA) receptor, in addition to other pharmacodynamics properties that include activity at sigma-1 receptors. Twenty patients with unipolar TRD who completed informed consent and met all eligibility criteria we enrolled in an open-label study of DM/Q up to 45/10mg by ...Dec 15, 2023 · The average milk concentration of the active metabolite dextrorphan at that time was 14 mcg/L (95% CI 10.7 to 17.9 mcg/L). These values translated to average “worst-case” daily infant dosages of 0.33 mcg/kg and 1.8 mcg/kg, and relative infant dosages of 0.07% and 0.41% for dextromethorphan and dextrorphan, respectively. severe headache; or. severe dizziness or anxiety, feeling like you might pass out. Common side effects of Coricidin HBP Chest Congestion and Cough may include: dizziness, drowsiness; sleep problems ( insomnia ); diarrhea; or. feeling nervous, restless, anxious, or irritable. This is not a complete list of side effects and others may occur.Koffex DM: Dextromethorphan belongs to a group of medications called antitussives (cough suppressants). This medication works by suppressing dry, hacking coughs. It is usually used for a short term to control coughing associated with the flu, a cold, or due to inhaled irritants.

How to use Delsym. Take this medication by mouth, usually every 4 to 12 hours as needed or as directed by your doctor. If stomach upset occurs, take with food or milk. Use a medication-measuring ...brompheniramine cetirizine. Applies to: Dimetapp Children's Cold & Cough (brompheniramine / dextromethorphan / phenylephrine) and Zyrtec (cetirizine) Using cetirizine together with brompheniramine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people, especially the elderly, may also …Common side effects of dextromethorphan and quinidine may include: dizziness, weakness; diarrhea, gas, vomiting; swelling in your hands or feet; flu symptoms, cough; or. abnormal liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.1. Dextromethorphan có tác dụng gì? Ho là một phản xạ của cơ thể giúp loại bỏ các chất bài tiết, chất kích thích hoặc là một trong các biểu hiện của bệnh lý. Ho có thể là biểu hiện của bệnh lý đường hô hấp nhưng cũng … Dextromethorphan is an over-the-counter (OTC) cough suppressant used to relieve coughing caused by the common cold, flu, or other illnesses. Common side effects of dextromethorphan include dizziness, lightheadedness, drowsiness, sedation, nervousness, restlessness, confusion, nausea, vomiting, stomach pain, and constipation. Dextromethorphan is not addictive but has potential for abuse ... They differ because Mucinex D also contains pseudoephedrine, a nasal decongestant, while Mucinex DM contains dextromethorphan, a cough suppressant. Also, Mucinex DM is available over-the-counter (OTC), while Mucinex D is sold behind the counter, requires ID, and can only be purchased in limited quantities without a prescription.Dizziness. Feeling nervous and excitable. Trouble sleeping. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to your national health agency.What is Capron DM? Dextromethorphan is a cough suppressant and pyrilamine is an antihistamine.. Capron DM is a combination medicine used to treat cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.. Capron DM will not treat a cough that is caused by smoking, asthma, or emphysema.. Capron DM may also be used for purposes not listed in this ...

There are 544 drugs known to interact with Bromfed DM (brompheniramine / dextromethorphan / pseudoephedrine), along with 10 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 85 are major, 451 are moderate, and 8 are minor. ... Zyrtec (cetirizine) Bromfed DM alcohol/food interactions. There are 2 …What is Capron DM? Dextromethorphan is a cough suppressant and pyrilamine is an antihistamine.. Capron DM is a combination medicine used to treat cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.. Capron DM will not treat a cough that is caused by smoking, asthma, or emphysema.. Capron DM may also be used for purposes not listed in this ...Jun 27, 2018 ... ... antihistamine for congestion, and they'll have a cough suppressant. ... antihistamine and dextromethorphan, you're only compounding those effects.The dose for the second plateau is between 2.5 and 7.5 mg/kg. This works out to between 200 and 550 mg DXM. The second plateau is very different from the first. At this dose, the effects feel much more similar to alcohol but with a pronounced reduction in cognitive function. People at this stage feel drunk.

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Benzonatate is a prescription, non-narcotic antitussive medication. It numbs the airways, the air sacs in the lungs, and the lining of the lungs. It's FDA-approved for adults and children over 10 years old. You can take up to 600 mg daily, divided into three doses or as otherwise recommended by your healthcare provider.Dec 21, 2023 · Maximum dose: 30 mg in 24 hours. 6 to 12 years: Immediate-release: 5 to 10 mg orally every 4 hours or 15 mg orally every 6 to 8 hours. Extended-release: 30 mg every 12 hours. Maximum dose: 60 mg in 24 hours. 12 years or older: Immediate-release: 10 to 20 mg orally every 4 hours or 30 mg orally ever 6 to 8 hours. Dextromethorphan HBr 30 mg - Cough Suppressant; Doxylamine Succinate, USP 12.5 mg - Antihistamine. ⚬This product contains the active ingredient ...Cetirizine (Zyrtec) Fexofenadine (Allegra) Diphenhydramine (Benadryl) Cough Medications With Eliquis. I'll lump both dextromethorphan, a cough suppressant, and guaifenesin, an expectorant, in this category. Both of these drugs are safe to take with Eliquis as there are no known drug interactions.

Applies to: Daytime Cold and Flu Relief (acetaminophen / dextromethorphan / pseudoephedrine) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or …Generic name: dextromethorphan and guaifenesin [ DEX-troe-meth-OR-fan-and-gwye-FEN-e-sin ] Brand names: Alka-Seltzer Plus Maximum Strength, Children Giltuss Cough and Chest Congestion, Children's Delsym Cough+Chest Congest DM, Children's Robitussin Cough and Chest, Children's Robitussin Cough and Chest Congestion DM, ...Jun 26, 2023 · Dextromethorphan is a drug used in many over-the-counter cough and cold medicines for its antitussive effects.[1] It comes in oral strips, lozenges, liquids, or liquid-filled capsules and formulations often combine the drug with guaifenesin, acetaminophen, and pseudoephedrine.[1] Dextromethorphan is also a commonly abused drug because of its euphoric, hallucinogenic, and dissociative ... Auvelity works by combining two other drugs into one medication. Dextromethorphan is an older drug that has some modulating effects. The other drug in the combination, buproprion, is an antidepressant in its own right. However, the purpose of bupropion in this medication is to slow the metabolism of dextromethorphan.Pets with multiple and/or serious health problems often end up taking many medications, which increases their risk for adverse reactions. Learn more about some of the drugs that can be involved in adverse interactions and what can be done to protect our pets.Taking too much dextromethorphan can cause serious side effects, such as fast heartbeat, slow breathing, confusion, or seizures. Store dextromethorphan (Delsym) up and away and out of children's reach and sight. Always put medication away every time you use it.dextromethorphan. A total of 340 drugs are known to interact with dextromethorphan. Dextromethorphan is in the drug class antitussives. Dextromethorphan is used to treat Cough. Zyrtec. A total of 256 drugs are known to interact with Zyrtec. Zyrtec is in the drug class antihistamines.Deconex DMX dextromethorphan hydrobromide 17.5 mg / guaifenesin 400 mg / phenylephrine hydrochloride 10 mg (POLY 730) View larger images. Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

Each 10 mL contains 20 mg of dextromethorphan, 200 mg of guaifenesin, and 10 mg of phenylephrine. Adults and children age 12 years and older: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours. Don't use more than 6 doses (60 mL) in a 24-hour period. Children under 12 years: Ask your child's provider.

Apr 20, 2019 · Zyrtec-D contains two active ingredients: Cetirizine. Pseudoephedrine. Mucinex DM also contains two active ingredients: Guaifenesin. Dextromethorphan. Cetirizine is a second-generation antihistamine, which differ from first-generation antihistamines (like Benadryl) in many respects. How Auvelity (dextromethorphan / bupropion) works. Auvelity (dextromethorphan / bupropion) is a combination of two medications: Dextromethorphan is an N-methyl-D-aspartate (NMDA) receptor antagonist (meaning it blocks the receptor) and a sigma-1 receptor agonist (meaning it attaches to the receptor). By blocking or activating certain receptors, it's thought that dextromethorphan raises ...dextromethorphan food. Applies to: Delsym Children's 12-Hour Cough Relief (dextromethorphan) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or …Promethazine is a phenothiazine that works like an antihistamine. It blocks the effects of a certain natural substance (histamine), which causes allergy symptoms. It also has a drying effect. Dextromethorphan belongs to a class of drugs known as cough suppressants. It acts on a part of the brain (cough center) to reduce the need to cough.Dextromethorphan/bupropion ( DXM/BUP ), sold under the brand name Auvelity, is a combination medication for the treatment of major depressive disorder (MDD). [1] Its active components are dextromethorphan (DXM) and bupropion. [1] Patients who stayed on the medication had an average of 11% greater reduction in depressive symptoms than placebo in ...CHEMICAL NAME. DXM is a widely available over-the-counter cough suppressant. When taken far above its standard medical dosage, it is a strong dissociative used primarily by teens. Many DXM-containing products (such as Coricidin Cough and Cold) also contain other active ingredients which can be dangerous or fatal in high doses.The average change in MADRS scores after six weeks was greater with dextromethorphan/bupropion than with bupropion (-13.7 points vs -8.8 points, 95% confidence interval [CI] = -3.1, -6.8), and ...The dose for the second plateau is between 2.5 and 7.5 mg/kg. This works out to between 200 and 550 mg DXM. The second plateau is very different from the first. At this dose, the effects feel much more similar to alcohol but with a pronounced reduction in cognitive function. People at this stage feel drunk.The cough suppressant (dextromethorphan) relieves the intensity and frequency of coughs. Standard Mucinex DM dosage for wet or dry cough: 600/30-1200/60 mg (one to two regular-strength tablets or one maximum strength tablet) every 12 hours. Maximum Mucinex DM dosage for wet or dry cough: 1200/60 mg (two regular-strength tablets or one maximum ...Objectives: To compare the effects of a single nocturnal dose of buckwheat honey or honey-flavored dextromethorphan (DM) with no treatment on nocturnal cough and sleep difficulty associated with childhood upper respiratory tract infections. Design: A survey was administered to parents on 2 consecutive days, first on the day of presentation when no medication had been given the prior evening ...

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Dextromethorphan and bupropion comes as a tablet to take by mouth with or without food. Initially, it is usually taken once a day for 3 days. After 3 days, it is usually taken twice a day (at least 8 hours apart). Take dextromethorphan and bupropion at around the same time (s) every day.Related/similar drugs mometasone nasal, Bromfed DM, brompheniramine / dextromethorphan / pseudoephedrine, Nasonex 24HR Allergy, Mucinex D, Advil Cold and Sinus, Vicks Dayquil Cold & Flu Relief Warnings. Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid ...Related/similar drugs Bromfed DM, brompheniramine / dextromethorphan / pseudoephedrine, Mucinex D, Vicks Dayquil Cold & Flu Relief, Vanacof Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup - Clinical Pharmacology. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines.Apr 21, 2020 · Dextromethorphan, which is in Robitussin and Mucinex DM, may be safe to use while pregnant. Still, check with your doctor before taking it. More research is needed on using dextromethorphan while ... Applies to: Mucinex Nightshift Sinus (acetaminophen / dextromethorphan / phenylephrine / triprolidine) and Zyrtec (cetirizine) Using cetirizine together with triprolidine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking ...Shop & learn more about Dextromethorphan Hbr at CVS Pharmacy. Discover our selection of products containing dextromethorphan hbr and enjoy FREE shipping on most orders.Dextromethorphan is a widely available over-the-counter antitussive that produces intoxicating, hallucinogenic, and dissociative effects at doses significantly exceeding the therapeutic range. We report the deaths of five teenage males in three incidents in three states (WA, FL, and VA) who purposefully ingested large doses of dextromethorphan ...Zyrtec-D can also cause these additional side effects: increased heart rate. feeling jittery. not feeling tired at bedtime. Zyrtec or Zyrtec-D can also cause serious side effects. Call your child ...Children's Zyrtec. Children's Mucinex Cough contains two ingredients: Dextromethorphan. Guaifenesin. Children's Zyrtec contains one: Cetirizine. All three of these drugs are considered to be safe together. There is no known interaction between them. Therefore, in this case, you should be fine giving Children's Zyrtec with Children's Mucinex Cough. ….

You've probably seen guaifenesin on cold medication labels for products like Mucinex and Robitussin. Guaifenesin is an expectorant, an agent best for treating a cough that produces mucus ...DXM uses a lot of CYP3A4 so terfenadine can't become the other drug and stays like terfenadine, very cardiotoxic. Do not do that. ... It might affect DXM metabolism just a little bit. Zyrtec (Cetirizine) It is notably not metabolized by the cytochrome P450 system. Best option. It can be yes-drowsy for some people though, so experience it before ...Dextromethorphan, or DXM, a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug and entheogen for its dissociative effects. [1] It has almost no psychoactive effects at medically recommended doses. However, dextromethorphan has powerful dissociative properties when ...Best Answer. I'm afraid that, even though it's unlikely it would be serious, the pseudoephedrine in the Zyrtec D and the dextromethorphan in the Mucinex could interact with each other. However ...Uses. This combination medication is used to temporarily treat runny nose, coughing, and sneezing caused by the common cold, allergies, hay fever, and other breathing illnesses. Promethazine is a ...Introduction: The ability of dextromethorphan to potentiate serotonin levels and lead to serotonin syndrome is well known but few case reports are published. The lack of published cases suggests therapeutic doses of these drugs are not enough to cause serotonin syndrome. We present two cases of serotonin syndrome associated with supra-therapeutic doses of dextromethorphan and therapeutic ...Use Robitussin DM (guaifenesin and dextromethorphan liquid) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food. Take with food if it causes an upset stomach . Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.Dosage/Direction for Use. Adult to childn 12 yr 10 mL every 6 hr. Childn 6 to <12 yr 5 mL every 6 hr. Do not exceed 4 doses in any 24-hr period. Childn 2 to <6 yr 2.5 mL/dose. Max: 10 mL daily. Click to view Robitussin-DM detailed prescribing information.Dextromethorphan (DXM) is a dissociative with a more complex pharmacology than ketamine and PCP. In medicine it's been used for cough, pain, pseudobulbar aff...Robitussin DM is a cough medicine for treating your cold or flu. Here's what you need to know, including how it works, the forms it comes in, as well as side effects, interactions, and warnings. Dextromethorphan and zyrtec, dextromethorphan food. Applies to: Mucinex DM (dextromethorphan / guaifenesin) Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated ..., Calls to Poison Control regarding DXM have increased dramatically since 2006. If you suspect someone has taken too much dextromethorphan, immediately check the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Mary Elizabeth May, RN, BA, MPH, CSPI., The active ingredients in NyQuil are acetaminophen, dextromethorphan HBr and doxylamine succinate. NyQuil also contains a number of inactive ingredients., Dextromethorphan received FDA approval in 1958 for its use as a cough suppressant. It is one of the most common compounds found in most over-the-counter antitussives for the past 50 years. In 2010, the FDA approved the use of dextromethorphan for pseudobulbar affect in combination with quinidine. This activity will highlight the mechanism of action, adverse event profile, approved and off ..., Robitussin DM is available in a pill form. When you're dosing that, there are two parts: Guaifenesin and dextromethorphan. You dose based on the Guaifenesin. So the dose for Guaifenesin in dogs is 3-5mg per kg up to every 4 hours. (wow!) If you have a tablet that's 100mg Guaifenesin, you leave the Dextromethorphan out of the equation and ..., Objectives: To compare the effects of a single nocturnal dose of buckwheat honey or honey-flavored dextromethorphan (DM) with no treatment on nocturnal cough and sleep difficulty associated with childhood upper respiratory tract infections. Design: A survey was administered to parents on 2 consecutive days, first on the day of presentation when no medication had been given the prior evening ..., Allegra is less likely to make you drowsy. Zyrtec and Allegra work faster than Claritin. All three work well to treat hives and symptoms of hay fever. This article compares Allegra, Claritin, and Zyrtec by looking at how quickly they work, recommended dosages, and side effects., Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan., Dextromethorphan --- Used for dry, hacking cough Runny Nose Sneezing Itchy/Watery Eyes (Allergy like Symptoms) Loratadine (Claritin®, Alavert®) Cetirizine (Zyrtec®)—may make you drowsy Cromolyn Sodium nasal spray (NasalCrom®) Diphenhydramine (Benadryl®)--- May make you drowsy, How to use Robitussin Pediatric 7.5 Mg/5 Ml Oral Syrup. Take this medication by mouth, usually every 4 to 12 hours as needed or as directed by your doctor. If stomach upset occurs, take with food ..., cetirizine food. Applies to: Zyrtec (cetirizine) Alcohol can increase the nervous system side effects of cetirizine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cetirizine., Clashes between ethnic Oromos and ethnic Somalis in the country’s dry and mainly pastoralist south-east have claimed 30 lives and displaced hundreds Addis Ababa The federal republi..., Although currently available antidepressants increase monoamine levels soon after the start of treatment, therapeutic benefits are often delayed by several weeks and the majority of patients with major depressive disorder fail to achieve an adequate response to first- or second-line therapies target …, Cyclobenzaprine ( Amrix , Flexeril) Orphenadrine. Prostate cancer medications. Flutamide ( Eulexin) Leuprolide ( Eligard , Lupron) Chemotherapy drugs. Busulfan ( Busulfex, Myleran ..., Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect. Ann Neurol. 2010;68(5):693-702. doi: 10.1002/ana.22093. 30. Dubovsky SL. Dextromethorphan/quinidine for pseudobulbar affect., DayQuil, a popular over-the-counter cold and flu remedy, contains ingredients like acetaminophen, dextromethorphan, and phenylephrine. On the other hand, Zyrtec is an antihistamine commonly used to alleviate allergy symptoms such as …, The management of DXM poisoning is primarily supportive. (See "Dextromethorphan misuse and poisoning: Clinical features and diagnosis", section on 'Clinical features' .) In addition, to careful assessment and support of airway, breathing, and circulation as needed, the clinician should anticipate and aggressively manage dissociative signs and ..., Zyrtec (Cetirizine) is an antihistamine medication which controls certain types of allergic symptoms (1). NyQuil, on the other hand, is a cold and flu medication which contains Acetaminophen, Dextromethorphan, and Doxylamine (2)., Jun 27, 2018 ... ... antihistamine for congestion, and they'll have a cough suppressant. ... antihistamine and dextromethorphan, you're only compounding those effects., When giving cough and cold medicine to children over 2 years of age, parents and caregivers should use caution. A meeting about the safety and effectiveness of cough and cold drug product use in ..., What is Delsym 12 Hour Cough Relief? Delsym 12 Hour Cough Relief is a cough suppressant that is used to treat cough caused by the common cold or flu.. Delsym 12 Hour Cough Relief will not treat a cough caused by smoking, asthma, or emphysema.. There are many brands and forms of dextromethorphan available. Not all brands are listed on this leaflet., Taking too much dextromethorphan can cause serious side effects, such as fast heartbeat, slow breathing, confusion, or seizures. Store dextromethorphan (Delsym) up and away and out of children's reach and sight. Always put medication away every time you use it., severe dizziness or anxiety, feeling like you might pass out. Common side effects of dextromethorphan and guaifenesin may include: dizziness, drowsiness; sleep problems ( insomnia ); diarrhea; or. feeling nervous, restless, anxious, or irritable. This is not a complete list of side effects and others may occur., Dextromethorphan, a nonprescription antitussive found in some guaifenesin-containing preparations, is increasingly recognized as a substance of abuse by many youth and young adults. Renally excreted medications known to have poor solubility in urine have the potential to precipitate when ingested in large quantity, leading to acute obstruction ..., unusual excitement, nervousness, restlessness, or irritability. unusual sleepiness, weakness or drowsiness, extreme tiredness. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects., Dextromethorphan is a cough suppressant that affects a certain part of the brain, reducing the urge to cough. Decongestants help relieve stuffy nose and ear congestion symptoms., Dextromethorphan (Delsym) is a cough suppressant that is a common ingredient in several over-the-counter cough/cold products. Caution should be taken when using Paxil and dextromethorphan together. Both Paxil and dextromethorphan can increase serotonin levels in the body and has the potential of causing serotonin syndrome, a rare, but ..., Liều lượng - cách dùng: Người lớn & trẻ > 12 tuổi: 30mg/lần cách 6-8 giờ, tối đa 120mg/24 giờ. Trẻ 6-12 tuổi:15mg/lần, cách 6-8 giờ, tối đa 60mg/24 giờ. Trẻ 2-6 …, Find patient medical information for Phenergan W/Dextromethorphan oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings., Objectives: Coughing is a prevalent symptom of upper respiratory infections (URIs) that cause disturbance in the sleep of children and their parents. There is as yet no reliable treatment to control URIs and their related cough; however, drugs such as dextromethorphan (DM) and diphenhydramine (DPH) are now mainly used in the world., Maximum dose: 20 mL in 24 hours (promethazine 25 mg; dextromethorphan 60 mg) 12 years to 18 years: 5 mL orally every 4 to 6 hours. Maximum dose: 30 mL in 24 hours (promethazine 37.5 mg; dextromethorphan 90 mg) Comments: Each 5 mL contains promethazine 6.25 mg and dextromethorphan 15 mg., Abstract. Dextromethorphan is a nonopioid antitussive metabolized by cytochrome P450 2D6 (CYP2D6) to an active metabolite, dextrorphan. CYP2D6 is polymorphically expressed in humans, with 5 to 10% of Caucasians being homozygous deficient for the active form of the enzyme. In a pilot study, the authors investigated the pharmacologic effects of ..., cough suppressant Dextromethorphan Numerous Brands Decongestants/ Appetite suppressants (found in cough, cold, allergy, and sinus medicines) Pseudophedrine ... antihistamines. Cetirizine (Zyrtec®) may or may not have less risk. Topical eye or nose sprays/drops have the least risk of these side effects. non-prescription medications and …