Is fenbendazole safe for humans

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Is fenbendazole safe for humans. Jun 17, 2021 · Recently, benzimidazole compounds, including fenbendazole, have been reported to have antitumor activities, via tubulin binding [3, 4]. Fenbendazole is considered a promising therapeutic agent for several cancers; however, its safety and tolerability in humans has not yet been clarified, although safety data exist for various animals .

Feb 2, 2020 · A YouTube video of a US patient diagnosed with small cell lung cancer claimed he had been cured by fenbendazole (animal anthelmintic), while attending a clinical trial with other anti-cancer drug at the MD Anderson Cancer Center. When fenbendazole became difficult to obtain on the market, even the human anthelmintic (albendazole) was sold out.

The drug gets into the parasite’s gut and collapses the tubulin, starving the parasite to death. The study shows that mebendazole may act similarly in pancreatic … Fenbendazole Dosage for Humans (Cancer) 222mgs for 30-90kgs; 444mgs for 91-200kgs; Take the required amount of fenbendazole after a high fat meal daily for 6 days, skip on the seventh day and repeat weekly. Supporting Supplements: Vitamin E 800 U/I – daily after food. Bio-Available Curcumin 600 milligrams – twice daily after eating By Heal Navigator. Last Updated: November 20, 2023. Is Fenbendazole Safe for Humans? Safety, Uses, and Research Insights. Is Fenbendazole Safe For … A Fenbendazole-containing diet combined with supplemental high dose of vitamins was reported by Gao et al. to inhibit growth of a human lymphoma xenografted into scid mice ; it was unclear whether this reflected a direct effect of the drug on tumor cells or stimulation of host immune responses. Abstract. Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the drug's lack of toxic effects at therapeutic levels, yet various demonstrated physiologic effects have the potential to alter research outcomes.See full list on alternativemedicine.com From animal use to a mainstay treatment against intestinal worms in humans. One of the ongoing challenges with neglected tropical diseases (NTDs) is that …

Fenbendazole, often referred to as FenBen, is an anthelminthic medication initially developed to eliminate roundworms and pinworms in animals and humans. Although first introduced in 1961, it wasn't until 2002 that FenBen's potential as a cancer treatment was fortuitously discovered during a glioblastoma study at Johns Hopkins University. In ... Fenbendazole is a benzimidazole anthelmintic agent, with a broad antiparasitic range in animals such as dogs and pigs. The agent is also reported to exert antitumor effects and inhibit microtubule-associated tubulin polymerization, but its safety and tolerability profile in humans remains unclear. A …SAFE-GUARD® (fenbendazole) Canine Dewormer INTERNAL PARASITICIDE Product Description Fenbendazole 22.2% canine dewormer. For the treatment and control of Roundworms (Toxocara canis, Toxascaris leonina), Hookworms (Ancylostoma caninum, Uncinaria stenocephala), Tapeworms (Taenia pisiformis), and Whipworms (Trichuris …Small puppies bring joy and excitement to any household. They are full of energy, curiosity, and an eagerness to explore their surroundings. However, just like human babies, small ...Fenbendazole for Humans Fenbendazole (also known as fenben) is a veterinary medication used to treat parasites and worms such as tapeworms, hookworms, roundworms, and whipworms, in animals. It is commonly used under brand names like Panacur C and Safe-Guard. Recently, researchers have been experimenting with …Safe-Guard ® AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. The chickens were necropsied 7 to 8 days after the last treatment, and adult worms in the intestines and ceca of the chickens in the control and treated groups were counted to determine percent efficacy.Trichuris spp. are common helminths in NHP, and benzimidazoles and avermectins have both been used to treat these intestinal parasites. The current study compared the efficacy of fenbendazole and ivermectin against natural infection of Trichuris spp. in African green monkeys (Chlorocebus sabaeus).Anthelmintic-naive animals (n = 65) were randomly …A 1.25-lb container will treat 1250 lb body weight. 10 mg fenbendazole per kg body weight (4.54 mg per pound) For a ONE (1) DAY treatment, add SAFE-GUARD Equi-bits Top Dress Pellets to the daily ration at the rate of 1.0 pound for each 500 pounds body weight. A 1.25-lb container will treat 625 lb body weight. Feed for ONE (1) DAY as above.

Are you looking to revamp your living space without breaking the bank? Look no further than Habitat for Humanity’s items for sale. Habitat for Humanity is a non-profit organization...Safe-Guard (fenbendazole) oral drench removes and controls: Stomach worms, Lungworms, Hookworm, Nodular worms, etc., RESIDUE WARNING: Cattle must not be slaughtered within eight days following last treatment. For dairy cattle, the milk discard time is zero hours. A withdrawal period has not been established for this product in pre-ruminating ...Is Fenbendazole Safe for Humans? The most recent studies have also shown that Fenbendazole can potentially be beneficial to pancreatic, ovarian, and …Methyl N-(6-phenylsulfanyl-1H benzimidazol-2-yl) carbamate [Fenbendazole, FZ], a benzimidazole compound, is a safe and inexpensive anthelmintic drug possessing an efficient anti-proliferative ...

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Abstract. Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the …After crypto's chaotic year, here's what investors need to know about safe it is to hold digital assets like bitcoin. By clicking "TRY IT", I agree to receive newsletters and promo...Fenbendazole for Humans Fenbendazole (also known as fenben) is a veterinary medication used to treat parasites and worms such as tapeworms, hookworms, roundworms, and whipworms, in animals. It is commonly used under brand names like Panacur C and Safe-Guard. Recently, researchers have been experimenting with …For the control of large strongyles, small strongyles, and pinworms the recommended dose is 5 mg fenbendazole per kg body weight (2.27 mg fenbendazole per pound) in a one (1) day treatment. For the control of ascarids the recommended dose is 10 mg fenbendazole per kg body weight (4.54 mg fenbendazole per pound) in a one (1) day treatment.Nov 17, 2023 · The available toxicological information suggests that fenbendazole seems to be well tolerated in humans after oral exposure and has very few side effects. However, observations in humans are limited. Under normal conditions, pure fenbendazole appears in powder form, whitish color and has poor solubility in water. Sep 5, 2023 · Fenbendazole is a versatile medication frequently prescribed to treat parasitic infections in both animals and humans. It’s categorized under the benzimidazole group of drugs. Its primary function is to disrupt the energy-producing processes of the parasites, causing them to perish. Globally, parasitic infections pose a considerable health ...

Panacur C and Safe-guard brands are owned by MERCK, which is one of the world’s biggest corporations. OPTIONS Panacur C / Safe-guard’s Fenbendazole is designed as a veterinary medicine for various animals, hence it comes in a wide range of forms: powder packets, powder, liquid suspension, paste, pellets, and so on.Roundworms and hookworms may pose serious human health risks; regular deworming may help reduce those risks. ... safe-guard ® (fenbendazole) Canine Dewormer. For dogs only, 6 weeks and older. Drug Facts: Active ingredients (in each dosage unit): Fenbendazole Granules 22.2% (222 mg/g)Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the drug's lack of toxic effects ...Fenbendazole is a de-wormer for dogs that may have anti-cancer effects. Learn how it works, what are the side effects and how to use it as a complementary cancer treatment.Sep 10, 2023 ... It's dangerous for humans to take any drug made for animals, including ivermectin. ... Also, some of the inactive ingredients in an animal ...Advertisement Composting toilets have several positive attributes. They save water, they use no energy, they recycle human fecal waste in a safe, sustainable and sanitary fashion w...Fenbendazole, often referred to as FenBen, is an anthelminthic medication initially developed to eliminate roundworms and pinworms in animals and humans. Although first introduced in 1961, it wasn't until 2002 that FenBen's potential as a cancer treatment was fortuitously discovered during a glioblastoma study at Johns Hopkins University. In ...Safe-Guard ® AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. The chickens were necropsied 7 to 8 days after the last treatment, and adult worms in the intestines and ceca of the chickens in the control and treated groups were counted to determine percent efficacy.safe-guard ® (fenbendazole) Canine Dewormer. For dogs only, 6 weeks and older. Drug Facts: Active ingredients (in each dosage unit): Fenbendazole Granules 22.2% (222 mg/g) Uses: For the treatment and control of: Tapeworms (Taenia pisiformis) Roundworms (Toxocara canis, Toxascaris leonina) Hookworms (Ancylostoma caninum, Uncinaria …Habitat for Humanity is a non-profit organization that works to provide safe and affordable housing for people in need. As part of their mission, they offer a furniture pick up pro...Sep 12, 2023 · As for research in humans - there is currently no data available on its safety and effectiveness in those with cancer. As for animal-based research - the only study on fenbendazole and cancer was a 2012 study which found that fenbendazole did not affect tumor growth, invasion, or metastasis.[3] Even if there were some positive animal studies as ... When you want to invest, it can be tricky to know where to start, especially if you’d prefer to avoid higher risk stocks and markets that make the news every day. Read on to learn ...

Tippens did some research and learned the drug is considered safe for humans, with no serious side effects. ... centers around the world are conducting their own studies on fenbendazole and ...

Fenbendazole was originally designed to cure parasites by selectively blocking the synthesis of microtubules by binding to β-tubulin. This stops the polymerization of tubulin dimers in cells of parasites and causes parasite death. Surprisingly, it seems that fenbendazole as well as other benzimidazoles exhibit a similar effect against tumor ... Fenbendazole is a benzimidazole type of antiparasitic drug.28 It is safe and effective against many helminth parasites in animals. Fenbendazole inhibits glucose uptake in the parasites. Because of its wide range of activity, its high degree of efficacy, and its broad margin of safety, this anthelmintic is frequently prescribed by veterinarians. Dogs and cats have been eating pet food for years, but a growing trend has items such as rice, carrots and even salmon ending up in their bowls. Folks typically have the best of in...While fenbendazole is generally considered safe and well-tolerated, interactions with other medications can occur and are not always known, so you might want to consult with a health care professional. ... However, there is limited to no clinical evidence supporting fenbendazole’s effectiveness for treating arthritis in humans. The use of ...According to VetInfo, there are two main types of animal antibiotics that are safe for cats: bacteriostatic antibiotics and fungistatic antibiotics. There are also three human anti...Dear Lifehacker, Where I live, snow just covered the entire city but I still need to get to work. Are there ways I drive safely in extreme Winter weather, or should I just cross my ...Jan 23, 2024 · Fenbendazole (also called fenben) is a veterinary medicine used to treat worms and parasites in animals. It is often sold under the brand names Safe-Guard and Pancur. Is Fenbendazole Safe for Humans? The most recent studies have also shown that Fenbendazole can potentially be beneficial to pancreatic, ovarian, and colorectal cancer. As a result ... Join us on "Fenben Voices" for a captivating exploration into the history of fenbendazole, a drug that transcended its veterinary origins to emerge as a beacon of …Fenbendazole is a drug commonly used for to treat parasites and worms (roundworms, hookworms, whipworms, and some tapeworms) in animals (common brand names are Pancur and Safe-Guard). However, it has also recently been found to be helpful in humans with cancer, and is the primary ingredient in the Joe Tippens Protocol.To know if the consumption of pheasant tissue from animals that were previously treated with fenbendazole was safe for humans, these calculations were compared with the actual consumption data in the USA and Belgium (EU) and to food consumption values for edible tissues established by the FDA/EMA and using all the fenbendazole sulfone NOAELs ...

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Safe-Guard ® AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. The chickens were necropsied 7 to 8 days after the last treatment, and adult worms in the intestines and ceca of the chickens in the control and treated groups were counted to determine percent efficacy.I’m still taking Fenbendazole 3 days on, four days off, consistently. No vitamins! STANFORD now producing Fenbendazole in their lab for human study! I’m living proof of Fenbendazole treatment with no vitamins. ... 1gr pkg. This is extremely safe to take every day, no days off. No elevated liver enzymes with this protocol. Save your life and ...Fenbendazole is a versatile medication frequently prescribed to treat parasitic infections in both animals and humans. It’s categorized under the benzimidazole group of drugs. Its primary function is to disrupt the energy-producing processes of the parasites, causing them to perish. Globally, parasitic infections pose a considerable health ...Recently, benzimidazole compounds, including fenbendazole, have been reported to have antitumor activities, via tubulin binding [3, 4]. Fenbendazole is considered a promising therapeutic agent for several cancers; however, its safety and tolerability in humans has not yet been clarified, although safety data exist for various animals .Advertisement. Blogs and popular media have discussed using fenbendazole (brand names: Panacure, Safe-Guard), a drug used to deworm dogs, to treat cancer. While some studies on cells in petri dishes and in mice suggest that fenbendazole might have anti-cancer properties, no studies have been done in people and it’s not …Fenbendazole remains the drug of choice to treat pinworm infection in laboratory rodents. When fenbendazole was last reviewed (15 y ago), the literature supported the drug's lack of toxic effects ...Fenbendazole is a broad-spectrum antiparasitic active ingredient used in veterinary medicine in dogs, cats and livestock against internal parasites (roundworms, tapeworms).It is not used against agricultural and household pests. It belongs to the chemical class of the benzimidazoles.. Common name: FENBENDAZOLE. Type: …Requirements for Safe Houses - Safe houses come in different types: defensive and offensive. But what are the requirements that define an effective safe house? Advertisement A safe...Panacur ® (fenbendazole) Paste 10% contains the active anthelmintic, fenbendazole. The chemical name of fenbendazole is methyl 5-(phenylthio)-2-benzimidazole carbamate. ... NOT FOR USE IN HUMANS. KEEP OUT OF REACH OF CHILDREN. The Safety Data Sheet (SDS) contains more detailed occupational safety … ….

safe-guard ® (fenbendazole) Directions: The daily dose for Safe-Guard ® Canine is 50 mg/kg (22.7 mg/lb) of body weight. You should weigh your dog to make sure you are using the right dose; i.e. correct gram amount and appropriate number of pouches. Your dog must be treated with the following dose for 3 days in a row.Fenbendazole for humans causes the parasite to run out of energy by preventing it from using glucose as effectively. Starvation and eventual death of the parasite are caused by the lack of energy ...Fenbendazole is not often used to treat humans in the same way as mebendazole is. It is often used to treat animals infected with parasites such as hookworms, whipworms, roundworms, and certain forms of tapeworms. It originally debuted in scientific trials some years ago for treating cancer under the brand names Safe-Guard or Panacur.(iii) Limitations. Milk taken during treatment and for 96 hours after the last treatment must not be used for human consumption. Cattle must not be slaughtered ...Dec 2, 2020 · Fenbendazole is not intended for use by humans but there is a reported case where the drug has been successfully used to manage a parasitic condition known as visceral larva migrans. Toxicity Generally, poisoning with fenbendazole is unusual because the medication has a low toxicity and high safety margin and most animal species tolerate the ... Fenbendazole, like albendazole and mebendazole, is an anthelmintic. Anthelmintics are drugs used to treat infections with parasites, more commonly called “worms.” The difference between these medications is that albendazole and mebendazole are FDA-approved for use in humans and fenbendazole is only FDA-approved for use …Anti-cancer effects of fenbendazole in colorectal cancer cells. (A) The SNU-C5 and 5-FU-resistant SNU-C5 (SNU-C5/5-FUR) cells were mock-treated with dimethyl sulfoxide (DMSO) or treated with indicated concentrations of fenbendazole or albendazole for 3 days. The extent of cell viability was determined by MTT assay as described in Methods.As for research in humans - there is currently no data available on its safety and effectiveness in those with cancer. As for animal-based research - the only study on fenbendazole and cancer was a 2012 study which found that fenbendazole did not affect tumor growth, invasion, or metastasis.[3] Even if there were some positive animal …Anti-cancer effects of fenbendazole in colorectal cancer cells. (A) The SNU-C5 and 5-FU-resistant SNU-C5 (SNU-C5/5-FUR) cells were mock-treated with dimethyl sulfoxide (DMSO) or treated with indicated concentrations of fenbendazole or albendazole for 3 days. The extent of cell viability was determined by MTT assay as described in …Fenbendazole's rare negative effects and ongoing study make it safe for human consumption. Again, the medicine targets animal parasites but also treats and prevents human cancer. Fenbendazole is often used in combination with other cancer medicines. Is fenbendazole safe for humans, Fenbendazole, often referred to as FenBen, is an anthelminthic medication initially developed to eliminate roundworms and pinworms in animals and humans. Although first introduced in 1961, it wasn't until 2002 that FenBen's potential as a cancer treatment was fortuitously discovered during a glioblastoma study at Johns Hopkins University. In ..., Fenbendazole is a deworming medication used to treat infections caused by intestinal worms in dogs and puppies, and it can also be used to treat tapeworms in humans. The drug is not approved for use in humans, but it does have some medicinal uses. Fenbendazole is available under the trade name Panacur and is often used to …, When it comes to dealing with unwanted animals in your home or business, it’s important to choose a professional animal removal service. Not only will they be able to safely and hu..., Is nuclear power safe, or is it one of the more dangerous forms of energy production? Find out if nuclear power is safe in this article. Advertisement The 1927 song "Fifty Million ..., Description. Fenbendazole is a broad spectrum anthelmintic that is used to control a number of common equine parasites, including large strongyles (Strongylus edentatus, S. equinus, S. vulgaris), encysted early third stage (hypobiotic), late third stage and fourth stage cyathostome larvae, small strongyles, pinworms (Oxyuris equi), …, Are you looking to revamp your living space without breaking the bank? Look no further than Habitat for Humanity’s items for sale. Habitat for Humanity is a non-profit organization..., See full list on alternativemedicine.com , Feb 25, 2016 · Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be administered ... , Heal Navigator is the largest resource for alternative cancer clinics and alternative cancer treatments. Learn more about us here., The Food and Drug Administration has not approved fenbendazole to treat or prevent cancer in humans. Some peer-reviewed studies have found potential in fenbendazole, a dog deworming drug, in ..., Nov 20, 2023 · The jury is still out on Fenbendazole’s safety and efficacy in humans. While its potential anti-cancer properties are intriguing, it’s crucial to approach with caution. Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. Our Integrative oncology nurses can ... , Fenbendazole is a versatile medication frequently prescribed to treat parasitic infections in both animals and humans. It’s categorized under the benzimidazole group of drugs. Its primary function is to disrupt the energy-producing processes of the parasites, causing them to perish. Globally, parasitic infections pose a considerable health ..., Fenbendazole is an antiparasitic drug that is used to treat parasitic infections in animals. The results of some studies suggest that fenbendazole can slow down cancer cell growth in cell cultures and animals. While researchers consider further research on fenbendazole’s potential anticancer effects to be important in finding new drugs for …, Summary. 83 year old female with metastatic breast cancer in lungs, liver, kidneys, spleen, pancreas, gall bladder and bones (spine, ribs, pelvis). Refused traditional chemotherapy and radiation. Took fenbendazole 222 mg 5 times per week for 8 months. Added targeted spot radiation of two tumors on spine causing pain., Safety Profile: Fenbendazole has a long history of safe use in animals, but its safety profile in humans is still being investigated. Limited studies and anecdotal reports suggest that fenbendazole may be generally well-tolerated when used off-label in humans. , A YouTube video of a US patient diagnosed with small cell lung cancer claimed he had been cured by fenbendazole (animal anthelmintic), while attending a clinical trial with other anti-cancer drug at the MD Anderson Cancer Center. When fenbendazole became difficult to obtain on the market, even the human anthelmintic (albendazole) was …, Fenbendazole is not primarily used by humans like mebendazole, It is a medication originally used for animals (mostly mammals, fishes, and birds) for the treatment of different kinds of parasitic ..., Food-grade barrels are plastic drums that are safe for storing and transporting human foods and potable water. Here are some places you can purchase food-grade barrels for a variet..., 779 reviews. Pure, tested, and trusted. With over 20 years of expertise, Fenben LAB brings the essence of purity in every capsule. 30 and 90 capsule bottles. >99% pure fenbendazol. Third party laboratory tested. Vegetarian capsules. Analysis report included. 60-day money back guaranteed. , Fenbendazole for Humans Fenbendazole (also known as fenben) is a veterinary medication used to treat parasites and worms such as tapeworms, hookworms, roundworms, and whipworms, in animals. It is commonly used under brand names like Panacur C and Safe-Guard. Recently, researchers have been experimenting with …, Fenbendazole (brand names Panacur and Safe-Guard) is a synthetic benzimidazole compound that acts as an antiparasitic drug against nematodes, cestodes, and trematodes. It’s also used to treat giardiasis in humans, which is a parasitic infection caused by the protozoan Giardia lamblia. Fenbendazole works by interfering with the parasite’s ..., Fenbendazole is a benzimidazole anthelmintic (kills worms large enough to be visible) and it has a broad spectrum (kills a wide variety of critters). It’s a compound with a wide safety margin. For example, when they tested very large doses on cats, they found no detectable side effects. Its chemical formula is C15H13N3O2S., When you have cancer, you need good nutrition to help keep your body strong. To do this, you need to be aware of the foods you eat and how you prepare them. Use the information bel..., 116 substances, fenbendazole and moxidectin, on the National List as parasiticides in organic livestock production 117 (NOP, 2011). A final rule established practice for the use of parasiticides and exemptions (uses) for fenbendazole 118 . and moxidectin (NOP, 2012): 119 . Under the authority of 7 U.S.C. 6501–6522. 120, While fenbendazole is generally considered safe and well-tolerated, interactions with other medications can occur and are not always known, so you might want to consult with a health care professional. ... However, there is limited to no clinical evidence supporting fenbendazole’s effectiveness for treating arthritis in humans. The use of ..., The available toxicological information suggests that fenbendazole seems to be well tolerated in humans after oral exposure and has very few side effects. However, observations in humans are limited. Under normal conditions, pure fenbendazole appears in powder form, whitish color and has poor solubility in water., Fenbendazole (brand names Panacur C ®, Safe-Guard ®) is a veterinary medication introduced in 1974. Worldwide, veterinarians commonly use fenbendazole, FBZ, to treat a variety of parasites in animals, such as tapeworms, hookworms, roundworms, lungworms, and whipworms. Fenbendazole has been known to have a high safety margin for animal use as ..., safe-guard ® (fenbendazole) Dewormer for Goats. Suspension 10% (100mg/mL) Withdrawal Periods and Residue Warnings: Goats must not be slaughtered for human consumption within 6 days following treatment. Because a milk discard time has not been established, do not use in lactating goats. Consult your veterinarian for assistance in the diagnosis ..., High degree of safety – Safe for foals, pregnant mares and older horses 1,3. Easy to administer – A unique apple-cinnamon flavor that horses readily accept 1. The Mode of Action of SAFE-GUARD (fenbendazole) Paste 10% is due to the inhibition of energy metabolism in the parasite 2. Available in two sizes: 25 gram and 92 gram., Apr 26, 2019 ... Report. 17:16. Go to channel · FENBENDAZOLE & ARTEMISININ I The Common Sense MD I Dr. Tom Rogers. Performance Medicine•218K views · 11:38. Go to&..., Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides., Fenbendazole is not primarily used by humans like mebendazole, It is a medication originally used for animals (mostly mammals, fishes, and birds) for the treatment of different kinds of parasitic ..., SAFE-GUARD® (fenbendazole) Canine Dewormer INTERNAL PARASITICIDE Product Description Fenbendazole 22.2% canine dewormer. For the treatment and control of Roundworms (Toxocara canis, Toxascaris leonina), Hookworms (Ancylostoma caninum, Uncinaria stenocephala), Tapeworms (Taenia pisiformis), and Whipworms (Trichuris vulpis) Pkg Size UPC # UIN # 1gm Single Box 021784470124 034906 1gm Display ...