Ondansetron and dramamine

We compare the side effects and drug effectiveness of Zofran odt and Dramamine from 127,783 people who take the 2 drugs. The phase IV clinical study is created by eHealthMe based on reports of people who take Zofran odt and/or Dramamine from sources including the FDA, and is updated regularly.

Dimenhydrinate (Dramamine) Diphenhydramine (Benadryl) Meclizine (Antivert) Anticholinergic agent: ... Promethazine (Phenergan) is similar in efficacy to ondansetron (Zofran), and oral ...Dramamine for Kids. A total of 380 drugs are known to interact with Dramamine for Kids. Dramamine for kids is used to treat the following conditions: Motion Sickness; Nausea/Vomiting; Zofran. A total of 347 drugs are known to interact with Zofran. Zofran is in the drug class 5HT3 receptor antagonists.Compare Meclizine vs Ondansetron head-to-head with other drugs for uses, ratings, cost, side effects and ... D-Vert, Dramamine All Day Less Drowsy, Dramamine II, Dramamine Less Drowsy, Driminate II, Help I'm Nauseous, Motion-Time, Sea-Calm, Travel Sickness, Travel-Ease View more: N/A. Half Life The half-life of a drug is the time taken for the ...The app is exposing the world to a side of Islam that is often overshadowed by extremisms. As the holy month of Ramadan approaches its end on July 17, Muslims the world over are ob...The researchers looked at 25 medications from seven drug classes to see which were most helpful for easing migraines. After triptans, the next most helpful drug classes were ergots such as dihydroergotamine (Migranal, Trudhesa) and anti-emetics such as promethazine (Phenergan). The latter help ease nausea, another common migraine …Dramamine is an antiemetic, which means it prevents vomiting. It is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is also an antihistamine that works by blocking receptors in your gut that trigger nausea in the brain.

Summary: We compare the side effects and drug effectiveness of Ondansetron and Dramamine from 127,752 people who take the 2 drugs. The phase IV clinical study is created by eHealthMe based on reports of people who take Ondansetron and/or Dramamine from sources including the FDA, and is updated regularly.The prophylactic administration of dimenhydrinate (Dramamine) is as effective as the use of ondansetron (Zofran) in preventing postoperative nausea and vomiting (PONV) in patients undergoing ...A migraine cocktail is a combination of medications that’s given in a medical setting to treat severe migraine symptoms. The exact medications used in a migraine cocktail can vary, but it ... Good evening. Thank you for using JustAnswer.Yes, it is fine to use both dramamine and ondansetron. There are no interactions between the two. Customer. Thank you! Dr. Megan, Expert. You're very welcome. Happy to help you.Have a nice evening. :) Online Primary Care Doctors Accepting New Patients. $44 video appointments available today with a membership as low as $15/month. Book a Video Appointment. Didn't find what you're looking for? 90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Ask your question.

Summary: We compare the side effects and drug effectiveness of Ondansetron and Dramamine from 127,752 people who take the 2 drugs. The phase IV clinical study is created by eHealthMe based on reports of people who take Ondansetron and/or Dramamine from sources including the FDA, and is updated regularly.Dec 14, 2015 · Two randomized, controlled trials involving patients with sea- or laboratory-induced motion sickness found no difference between ondansetron and placebo, however. 42,43 Levine and colleagues have suggested that ondansetron may be ineffective because of its site of action, as it works at the vagal afferent receptor or the chemoreceptor trigger ... Zofran (ondansetron) Zyrtec (cetirizine) Dramamine for Kids alcohol/food interactions. There is 1 alcohol/food interaction with Dramamine for Kids (dimenhydrinate). Dramamine for Kids disease interactions. There are 5 disease interactions with Dramamine for Kids (dimenhydrinate) which include: prematurity; anticholinergic effects; asthma/COPD ...• If options above fail, consider a 5HT3 antagonist (e.g. Ondansetron, 4 to 8 mg po daily to BID PRN). • Note: Ondansetron is very expensive; consider risk of QT prolongation in the setting of possible electrolyte abnormalities. • For patients with gastric stasis/gastroparesis, consider metoclopramide 5 mg po QIDPrescribed for Nausea/Vomiting, Motion Sickness. Dramamine Original Formula may also be used for purposes not listed in this medication guide. Prescription only. Ondansetron may be used for the prevention or treatment of nausea and vomiting but it may cause constipation or a headache.

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The ondansetron-treated group showed a greater need for re-administration of the medication (50.6% vs. 27.1%). The relief score was significantly higher in the ondansetron-treated group compared with the group received promethazine (P < 0.001). The time to become asymptomatic showed no statistically significant difference between groups (p = …Get ratings and reviews for the top 11 roofers in San Bernardino, CA. Helping you find the best roofers for the job. Expert Advice On Improving Your Home All Projects Featured Cont...We last polled our network of investors on the topic of gaming infrastructure startups back in May just as it was becoming clear what pandemic opportunities were in store for gamin...Dimenhydrinate has an average rating of 8.9 out of 10 from a total of 77 ratings on Drugs.com. 88% of reviewers reported a positive effect, while 8% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 16% reported a negative effect.Wall Street careers continue to attract students from America’s elite universities. With thousands of graduates jostling to break into the industry, it has become increasingly diff...Ondansetron (Zofran) Granisetron (Sustol, Sancuso) Dolasetron (Anzemet) Palonosetron (Aloxi) Neurokinin (NK-1) receptor antagonists. These medications help to suppress the vomiting reflex. These ...

The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help …Take a tour of the Guest House at Graceland, a new hotel operated by Elvis Presley's Graceland in Memphis, Tenn. By clicking "TRY IT", I agree to receive newsletters and promotions...4 days ago · Descriptions. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. How to take it: Two 12-ounce doses, each followed by a quart of water. Prep: Sodium picosulfate, magnesium oxide, and citric acid (Prepopik). How to take it: Two 5-ounce doses, the first followed by five 8-ounce servings of clear liquid; the second followed by three 8-ounce servings of clear liquid. Prep: Polyethylene glycol, sodium sulfate ...Previous studies have evaluated promethazine, ondansetron (Zofran), corticosteroids, metoclopramide, and diphenhydramine (Benadryl), but no trial has directly compared metoclopramide and ...Zofran‚ also known by its generic name ondansetron‚ is a medication that has revolutionized the management of nausea and vomiting. It is commonly prescribed to prevent and treat nausea and vomiting caused by cancer drug treatment (chemotherapy)‚ radiation therapy‚ or after surgery.Can i take dramamine (zzzquil) and zofran (ondansetron) cream at the same time? doxycycline monohydrate is making me nauseous. A doctor has provided 1 answer. Dr. Al Hegab answered. Specializes in Allergy and Immunology?: I am not sure if there is zofran (ondansetron) cream available? At any rate one drug, dramamine, …Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness. 9, 10, 11 Dimenhydrinate is a combination of Diphenhydramine and 8-chlorotheophylline in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8 ...Dramamine has an average rating of 8.9 out of 10 from a total of 53 ratings on Drugs.com. 87% of reviewers reported a positive effect, while 8% reported a negative effect. Promethazine has an average rating of 7.3 out of 10 from a total of 380 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect.Prophylactic administration of dimenhydrinate is as effective as the use of ondansetron in preventing PONV in patients undergoing elective laparoscopic cholecystectomies and the potential drug cost savings exceed $7.25 million per year. BackgroundThe prophylactic administration of dimenhydrinate (Dramamine) is as effective as the use of ondansetron (Zofran) in preventing postoperative nausea ...Emetrol vs Zofran – Differences. Emetrol is an OTC medicine used to treat symptoms of nausea. Unlike antacids, it is intended specifically for nausea and works by quieting the stomach muscle contractions. Zofran (active ingredient – ondansetron) is a medication that belongs to the class of drugs called 5-HT3 receptor antagonists.

Side Effects. Drowsiness, constipation, blurred vision, or dry mouth /nose/throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To relieve dry ...

On May 11, Sumitomo Electric Industries will be releasing earnings for the most recent quarter.Wall Street predict expect Sumitomo Electric Indust... On May 11, Sumitomo Electric I...Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension. Paradoxical CNS stimulation in pediatric patients and occasionally in adults. With IM injection: Pain at the injection site. Because dimenhydrinate (the active ingredient contained in Dramamine ...Shade structures protect from heat and sun, making summer in your yard more enjoyable. With warmer weather and longer, sunnier days on the horizon, now is the time to get your yard...Other antihistamines. Meclizine (Antivert), diphenhydramine (Benadryl), and dimenhydrinate (Dramamine) all help relieve pregnancy-related nausea. A review of over 35 studies found these antihistamines to be safe. And, studies have found that they’re better than placebo at treating nausea in pregnancy. Lower-cost generic is available. Ratings & Reviews. Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 267 ratings on Drugs.com. 76% of reviewers reported a ... 4 days ago · Descriptions. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. On May 11, Sumitomo Electric Industries will be releasing earnings for the most recent quarter.Wall Street predict expect Sumitomo Electric Indust... On May 11, Sumitomo Electric I...Aug 24, 2017 ... My little Zofran pills — and other drugs like steroids and Ativan that amplify the anti-nausea effect — made it possible for me to get through ...Nausea is a common symptom in hospitalised patients. Multiple antiemetic medications have been associated with TDP including domperidone, 31, 32 ondansetron, 31 and prochlorperazine. 33 …Uses of Zofran for Kids. Zofran is approved for the prevention of nausea and vomiting in people undergoing chemotherapy or radiation. It is also approved to prevent postoperative (post-surgical) nausea and vomiting. Even so, Zofran is often prescribed off-label due to its potent antiemetic (anti-nausea) effects.

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Gravol, which is known more commonly as Dramamine in the United States, can be given to dogs with the dosage depending on the amount a dog weighs. A veterinarian will be able to re...Prochlorperazine [Compazine] and diphenhydramine [Benadryl] c. Ondansetron [Zofran] and dimenhydrinate [Dramamine] d. Aprepitant [Emend] and ondansetron [Zofran Regimens for preventing CINV may include medications such as a serotonin receptor antagonist (ondansetron); the substance P/neurokinin1 antagonist aprepitant; and a benzodiazepine ...Ondansetron is a serotonin-3 receptor antagonist, and Dramamine is an antihistamine. Side effects of ondansetron and Dramamine that are similar include drowsiness and constipation. Side effects of ondansetron that are different from Dramamine include headache, feeling unwell , fatigue, dizziness, diarrhea, and …Good evening. Thank you for using JustAnswer.Yes, it is fine to use both dramamine and ondansetron. There are no interactions between the two. Customer. Thank you! Dr. Megan, Expert. You're very welcome. Happy to help you.Have a nice evening. :)The dosage of Dramamine for motion sickness when pregnant or morning sickness is the same dosage as for those who are not pregnant. “Dimenhydrinate may be taken during pregnancy if recommended by an OB-GYN,” Dr. Pepin says. “A pregnant woman may take 25 mg to 50 mg every four to six hours as needed.”.Amazon's plan to buy prescription-management service PillPack is a bitter pill for companies like CVS Health and Walgreens. Amazon’s plan to push deeper into healthcare by acquirin...Emetrol vs Zofran – Differences. Emetrol is an OTC medicine used to treat symptoms of nausea. Unlike antacids, it is intended specifically for nausea and works by quieting the stomach muscle contractions. Zofran (active ingredient – ondansetron) is a medication that belongs to the class of drugs called 5-HT3 receptor antagonists.Jul 14, 2023 · Granisetron — Like ondansetron, granisetron is a 5-HT3 antagonist used primarily for prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery (including cesarean birth). It is available in oral, intravenous, and transdermal formulations. Its only advantage over ondansetron is transdermal availability. Dimenhydrinate is a theoclate salt composed of diphenhydramine, an ethanolamine derivative, and 8-chlorotheophylline, a chlorinated theophylline derivative, in a 1 : 1 ratio. Dimenhydrinate must be metabolized into its active ingredient diphenhydramine to attain antiemetic efficacy. Therefore dimenhydrinate has a slower onset of action and is ... ….

The dosage of Dramamine for motion sickness when pregnant or morning sickness is the same dosage as for those who are not pregnant. “Dimenhydrinate may be taken during pregnancy if recommended by an OB-GYN,” Dr. Pepin says. “A pregnant woman may take 25 mg to 50 mg every four to six hours as needed.”. Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. See also: Dramamine side effects in more detail. See also: meclizine side effects in more detail. We could not find an exact match for this medicine. Sep 5, 2023 · Anti-Nausea Medication in Pregnancy. Most Effective Anti-Nausea Medications. When to See a Healthcare Provider. Nausea is an uncomfortable or “queasy” feeling with or without the urge to vomit. How to treat nausea can be determined by its cause. Other antihistamines. Meclizine (Antivert), diphenhydramine (Benadryl), and dimenhydrinate (Dramamine) all help relieve pregnancy-related nausea. A review of over 35 studies found these antihistamines to be safe. And, studies have found that they’re better than placebo at treating nausea in pregnancy.Meclizine(non-drowsy Dramamine) is the holy grail for me. The patches put me on my ass for a whole day. I was so tired, I face planted in my dinner and then entered the most uncomfortable 16 hour sleep period. I had to take it off to even function. Zofran really only prevents me from throwing up instead of preventing nausea.Uses of Zofran for Kids. Zofran is approved for the prevention of nausea and vomiting in people undergoing chemotherapy or radiation. It is also approved to prevent postoperative (post-surgical) nausea and vomiting. Even so, Zofran is often prescribed off-label due to its potent antiemetic (anti-nausea) effects.a. Scopolamine [Transderm Scop] and lorazepam [Ativan] b. Prochlorperazine [Compazine] and diphenhydramine [Benadryl] c. Ondansetron [Zofran] and dimenhydrinate [Dramamine] d. Aprepitant [Emend] and ondansetron [Zofran Regimens for preventing CINV may include medications such as a serotonin receptor antagonist (ondansetron); …Ondansetron and Dramamine (dimenhydrinate) are anti-nausea medications used for different conditions. Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy and to prevent vomiting and nausea after surgery. Dramamine is used for prevention and treatment of symptoms associated with motion sickness …Acute vertigo is best treated with nonspecific medication such as dimenhydrinate (Dramamine®) and meclizine (Bonine®). These medications are eventually weaned as they can prevent healing over the long-term, explains Dr. Fahey. Vertigo that only occurs within the first five minutes of standing is typically due to blood pressure … Ondansetron and dramamine, I used 12.5mg Meclizine (Bonine or non-drowsy Dramamine) in the mornings, and took 2mg of Zofran or 12.5mg of Phenergan at night, because invariably I would get sick after dinner, we had really, really rough seas. I used Zofran ODT if I wanted to be more alert, Phenergan if I needed a good nights' sleep!, • If options above fail, consider a 5HT3 antagonist (e.g. Ondansetron, 4 to 8 mg po daily to BID PRN). • Note: Ondansetron is very expensive; consider risk of QT prolongation in the setting of possible electrolyte abnormalities. • For patients with gastric stasis/gastroparesis, consider metoclopramide 5 mg po QID, Background The prophylactic administration of dimenhydrinate (Dramamine) is as effective as the use of ondansetron (Zofran) in preventing postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic cholecystectomy. A prospective double-blind randomized study was performed in a tertiary care referral center. Methods …, Dec 5, 2022 · Let’s discuss six important Dramamine interactions and how to manage them. 1. Benzodiazepines. Benzodiazepines (BZDs) are used to treat conditions like anxiety and panic disorder. Some are also used to help you sleep. Examples include alprazolam (Xanax), lorazepam (Ativan), and temazepam (Restoril). , The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ..., Antihistamines such as meclizine (Antivert) are associated with minor side effects involving the central nervous system, such as confusion, sedation, dizziness, …, The neuroleptic drug droperidol is widely used for PONV prophylaxis and is comparable to ondansetron as a prophylactic antiemetic.37 For greatest efficacy, droperidol is administered at the end of surgery38 or concomitantly with morphine via patient-controlled analgesia (PCA) systems.39 The use of low doses. Table 5., Children 4 to 11 years of age—At first, 4 mg taken 30 minutes before starting cancer treatment. The 4-mg dose is taken again 4 and 8 hours after the first dose. Then, the dose is 4 mg every 8 hours for 1 to 2 days. Children younger than 4 years of age—Use and dose must be determined by your doctor., Lymphatic Filariasis is often known as elephantiasis. To learn all about Lymphatic Filariasis, see Lymphatic Filariasis page. Reviewed by a GP. Try our Symptom Checker Got any othe..., Summary. OTC dizziness medications may be helpful on some occasions, like preventing motion sickness and associated dizziness. However, they won’t be useful if the cause of your dizziness is due to something else, such as an inner ear issue, another medication you’re taking, or a bad migraine., A few OTC treatments are available that can be helpful in relieving nausea, vomiting, and dizziness. Dimenhydrinate (Dramamine) and meclizine (Bonine) are perennial favorites for treating symptoms associated with motion sickness. Emetrol (consisting of dextrose, fructose, and phosphoric acid), can be effective in treating nausea., Ondansetron 5-HT3 serotonergic antagonist Antiemetic 0.5 mg/kg PO or IV Q 12–24 H or 30 min before chemotherapy Doses up to 1 mg/kg IV Q 12–24 H are occasionally needed Pantoprazole Proton pump inhibitor Gastroprotective agent 0.7–1 mg/kg PO or IV Q 24 H Prochlorperazine Alpha-2 adrenergic antagonist D2 dopaminergic antagonist, The 5-HT 3 (serotonin) blocker ondansetron has been studied for treatment and prevention of motion sickness based on its antiemetic effects in patients receiving chemotherapy. ... Dramamine (dimenhydrinate) product information. Irvington, NY: Medtech Products, Inc; April 2012. 51. Benadryl (diphenhydramine) product information., Acute vertigo is best treated with nonspecific medication such as dimenhydrinate (Dramamine®) and meclizine (Bonine®). These medications are eventually weaned as they can prevent healing over the long-term, explains Dr. Fahey. Vertigo that only occurs within the first five minutes of standing is typically due to blood pressure …, Good evening. Thank you for using JustAnswer.Yes, it is fine to use both dramamine and ondansetron. There are no interactions between the two. Customer. Thank you! Dr. Megan, Expert. You're very welcome. Happy to help you.Have a nice evening. :), The term PONV describes nausea and/or vomiting in the post-anesthesia care unit (PACU) of a hospital or within 24 hours of undergoing inpatient surgery. Postdischarge nausea and vomiting (PDNV) refers to symptoms that occur 24 to 48 after discharge from an outpatient surgical procedure, including dental surgery., The dosage of Dramamine for motion sickness when pregnant or morning sickness is the same dosage as for those who are not pregnant. “Dimenhydrinate may be taken during pregnancy if recommended by an OB-GYN,” Dr. Pepin says. “A pregnant woman may take 25 mg to 50 mg every four to six hours as needed.”., Lymphatic Filariasis is often known as elephantiasis. To learn all about Lymphatic Filariasis, see Lymphatic Filariasis page. Reviewed by a GP. Try our Symptom Checker Got any othe..., We compare the side effects and drug effectiveness of Zofran odt and Dramamine from 127,783 people who take the 2 drugs. The phase IV clinical study is created by eHealthMe based on reports of people who take Zofran odt and/or Dramamine from sources including the FDA, and is updated regularly., Evidence-Based Answer. Scopolamine should be used to reduce nausea associated with motion sickness, but it does not reduce vomiting. (Strength of …, Clinical trials have shown that ondansetron, a commonly used antiemetic, is ineffective in preventing nausea associated with motion sickness. ... For children aged 2–12 years, dimenhydrinate (Dramamine), 1–1.5 mg/kg per dose, or diphenhydramine (Benadryl), 0.5–1 mg/kg per dose up to 25 mg, can be given 1 hour before travel and every 6 ..., Cream of tartar (“potassium bitartrate” if you’re nerdy) is a substance with many uses, but it’s stabilizing properties will help take your egg whites to new, resilient heights. Cr..., Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or ... , Uses of Zofran for Kids. Zofran is approved for the prevention of nausea and vomiting in people undergoing chemotherapy or radiation. It is also approved to prevent postoperative (post-surgical) nausea and vomiting. Even so, Zofran is often prescribed off-label due to its potent antiemetic (anti-nausea) effects., Ondansetron (Zofran) and the second-generation antihistamines cetirizine (Zyrtec) and fexofenadine (Allegra) do not reduce symptoms of motion sickness and should not be used. (SOR: B, based on ..., Meclizine has an average rating of 7.4 out of 10 from a total of 225 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 19% reported a negative effect. Scopolamine has an average rating of 5.6 out of 10 from a total of 207 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 38% reported a negative effect., 4 days ago · Descriptions. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. , Ondansetron. Over-the-counter. Prescribed for Nausea/Vomiting, Motion Sickness. Dramamine may also be used for purposes not listed in this medication guide. …, Store between 2° and 30°C (36° and 86°F). ZOFRAN Oral Solution, a clear, colorless to light yellow liquid with a characteristic strawberry odor, contains 5 mg of ondansetron HCl dihydrate equivalent to 4 mg of ondansetron per 5 mL in amber glass bottles of 50 mL with child-resistant closures (NDC 0173-0489-00)., Can i take claritin (loratadine) and dramamine at the same time? A doctor has provided 1 answer. wake up in the middle of the night, feeling. bloated and nauesous. which should i use transderm scop (scopolamine) or dramamine? or can i take both?: Nausea: Seems like you have been through this before. The transdermal. , Ondansetron (Zofran) and the second-generation antihistamines cetirizine (Zyrtec) and fexofenadine (Allegra) do not reduce symptoms of motion sickness and should not be used. (SOR: B, based on ..., Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or ... , Aug 30, 2007 ... You should try dramamine or antivert. Antivert is for those that have vertigo/motion sickness and can stop the nausea associated with that......